1QPE
STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | LCK KINASE | polymer | 279 | 32353.8 | 1 | UniProt (P06239) Pfam (PF07714) In PDB | Homo sapiens (human) | |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE | non-polymer | 302.8 | 1 | Chemie (PP2) | |||
| 4 | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A: 231 - 509 (UniProt: P06239)
| PDB | External Database | Details |
|---|---|---|
| Ptr 394 | Tyr 393 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32353.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 591.0 | |
| All* | Total formula weight | 32944.8 |
