1QE1
CRYSTAL STRUCTURE OF 3TC-RESISTANT M184I MUTANT OF HIV-1 REVERSE TRANSCRIPTASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | REVERSE TRANSCRIPTASE, SUBUNIT P66 | polymer | 558 | 64256.6 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus type 1 BH10 | RT |
| 2 | B (B) | REVERSE TRANSCRIPTASE, SUBUNIT P51 | polymer | 427 | 49893.3 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus type 1 BH10 | RT |
Sequence modifications
A: 1 - 558 (UniProt: P03366)
B: 1 - 427 (UniProt: P03366)
| PDB | External Database | Details |
|---|---|---|
| Ile 184 | Met 351 | engineered mutation |
| Ser 280 | Cys 447 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ile 184 | Met 351 | engineered mutation |
| Ser 280 | Cys 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114149.9 | |
| All* | Total formula weight | 114149.9 |
