1QBK

STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	KARYOPHERIN BETA2	polymer	890	102521.9	1	UniProt (Q92973) Pfam (PF03810) Pfam (PF02985) Pfam (PF13513)	Homo sapiens (human)
2	B (C)	RAN	polymer	216	24596.8	1	UniProt (P62826) Pfam (PF00071)	Homo sapiens (human)
3	C (C)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D (C)	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	1	Chemie (GNP)

Sequence modifications

B: 1 - 890 (UniProt: Q92973)

PDB	External Database	Details
Thr 217	Ile 217	conflict
Mse 175	Met 175	modified residue
Mse 210	Met 210	modified residue
Arg 237	Met 237	modified residue
Met 247	Met 247	modified residue
Mse 254	Met 254	modified residue
Mse 261	Met 261	modified residue
Mse 308	Met 308	modified residue
Mse 429	Met 429	modified residue
Mse 432	Met 432	modified residue
Mse 482	Met 482	modified residue
Mse 564	Met 564	modified residue
Mse 566	Met 566	modified residue
Mse 575	Met 575	modified residue
Mse 624	Met 624	modified residue
Mse 641	Met 641	modified residue
Mse 672	Met 672	modified residue
Mse 680	Met 680	modified residue
Mse 710	Met 710	modified residue
Mse 739	Met 739	modified residue
Mse 743	Met 743	modified residue
Mse 749	Met 749	modified residue
Mse 789	Met 789	modified residue
Mse 820	Met 820	modified residue
Mse 852	Met 852	modified residue

C: 1 - 216 (UniProt: P62826)

PDB	External Database	Details
Arg 129	Ser 129	conflict
Mse 89	Met 89	modified residue
Mse 179	Met 179	modified residue
Mse 189	Met 189	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	127118.7
Non-Polymers*	Number of molecules	2
	Total formula weight	546.5
All*	Total formula weight	127665.2

*Water molecules are not included.