1Q8K

Solution structure of alpha subunit of human eIF2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Eukaryotic translation initiation factor 2 subunit 1	polymer	308	35741.8	1	UniProt (P05198) Pfam (PF00575) Pfam (PF07541) In PDB	Homo sapiens (human)	Eukaryotic translation initiation factor 2 alpha subunit, eIF-2-alpha, EIF- 2alpha, EIF-2A

Sequence modifications

A: 4 - 302 (UniProt: P05198)

PDB	External Database	Details
Met 3	-	cloning artifact
Gln 27	Ala 27	engineered mutation
His 46	Leu 46	engineered mutation
Lys 71	Val 71	engineered mutation
Leu 303	-	cloning artifact
Glu 304	-	cloning artifact
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35741.8
All*	Total formula weight	35741.8

*Water molecules are not included.