1Q3U
Crystal structure of a wild-type Cre recombinase-loxP synapse: pre-cleavage complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (C, G) | loxP DNA | polymer | 37 | 11364.3 | 2 | |||
| 2 | B, D (D, H) | loxP DNA | polymer | 37 | 11387.4 | 2 | |||
| 3 | E, F, G, H (A, B, E, F) | Cre recombinase | polymer | 347 | 39066.7 | 4 | UniProt (P06956) Pfam (PF00589) | Enterobacteria phage P1 | GST-loxP-cre recombinase fusion protein; Retrofitting vector pRetroES |
| 4 | I, S (C, F) | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
| 5 | J, K, L, M, N... (C, D, G, H, A...) | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) | |||
| 6 | U, V (A, F) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B, E, F: 1 - 343 (UniProt: P06956)
| PDB | External Database | Details |
|---|---|---|
| Phe -3 | - | cloning artifact |
| Gln -2 | - | cloning artifact |
| Val -1 | - | cloning artifact |
| Pro 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 201770.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 496.9 | |
| All* | Total formula weight | 202267.1 |
