1Q3U

Crystal structure of a wild-type Cre recombinase-loxP synapse: pre-cleavage complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006310	biological_process	DNA recombination
A	0015074	biological_process	DNA integration
B	0003677	molecular_function	DNA binding
B	0006310	biological_process	DNA recombination
B	0015074	biological_process	DNA integration
E	0003677	molecular_function	DNA binding
E	0006310	biological_process	DNA recombination
E	0015074	biological_process	DNA integration
F	0003677	molecular_function	DNA binding
F	0006310	biological_process	DNA recombination
F	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 301

Chain	Residue
A	HIS40
A	LYS43
D	DT111

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 344

Chain	Residue
A	HIS269

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 346

Chain	Residue
D	DC106

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 347

Chain	Residue
A	ASP157

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG G 306

Chain	Residue
G	DG117

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG H 307

Chain	Residue
H	DC120

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 308

Chain	Residue
C	DG117

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	ARG173
E	HIS289
E	ARG292
E	TRP315
F	ARG173
F	HIS289
F	ARG292
F	TRP315
A	HIS289
A	ARG292
A	TRP315
B	ARG173
B	HIS289
B	ARG292
B	TRP315
E	ARG173

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: O-(3'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01246

Chain	Residue	Details
A	TYR324
B	TYR324
E	TYR324
F	TYR324

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