1Q3A
Crystal structure of the catalytic domain of human matrix metalloproteinase 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Stromelysin-2 | polymer | 165 | 18537.5 | 3 | UniProt (P09238) Pfam (PF00413) | Homo sapiens (human) | Matrix metalloproteinase-10, MMP-10, Transin-2, SL-2 |
| 2 | D, E, J, K, P... (A, B, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, G, H, L, M... (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 4 | I, O, U (A, B, C) | N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID | non-polymer | 316.4 | 3 | Chemie (NGH) | |||
| 5 | V, W, X (A, B, C) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B, C: 99 - 263 (UniProt: P09238)
| PDB | External Database | Details |
|---|---|---|
| Asn 170 | Phe 170 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 55612.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1702.3 | |
| All* | Total formula weight | 57314.7 |
