1PY5
Crystal Structure of TGF-beta receptor I kinase with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TGF-beta receptor type I | polymer | 326 | 37102.6 | 1 | UniProt (P36897) Pfam (PF08515) Pfam (PF00069) | Homo sapiens (human) | TGFR-1, TGF-beta type I receptor, Serine/threonine-protein kinase receptor R4, SKR4, Activin receptor-like kinase 5, ALK-5 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | 4-(3-PYRIDIN-2-YL-1H-PYRAZOL-4-YL)QUINOLINE | non-polymer | 272.3 | 1 | Chemie (PY1) | |||
| 4 | D (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37102.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 37471.0 |
