1PXG
Crystal structure of the mutated tRNA-guanine transglycosylase (TGT) D280E complexed with preQ1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase | polymer | 382 | 42450.2 | 1 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis | tRNA-guanine transglycosylase, Guanine insertion enzyme |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 7-DEAZA-7-AMINOMETHYL-GUANINE | non-polymer | 179.2 | 1 | Chemie (PRF) | |||
| 4 | D, E, F, G, H... (A) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | L (A) | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A: 2 - 383 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Glu 280 | Asp 279 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42450.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 981.3 | |
| All* | Total formula weight | 43431.5 |
