1PX7
A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to glutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutathione S-transferase P | polymer | 209 | 23260.6 | 2 | UniProt (P09211) Pfam (PF02798) Pfam (PF14497) In PDB | Homo sapiens (human) | pi Glutathione Transferase, GST class-pi, GSTP1-1 |
| 2 | A, B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 3 | A, B | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 4 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 418 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 209 (UniProt: P09211)
| PDB | External Database | Details |
|---|---|---|
| Glu 152 | Asp 152 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46521.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1045.2 | |
| All* | Total formula weight | 47566.4 |
