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1PW6

Low Micromolar Small Molecule Inhibitor of IL-2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BInterleukin-2polymer13315436.02UniProt (P60568)
Pfam (PF00715)
In PDB
Homo sapiens (human)IL-2, T-cell growth factor, TCGF, Aldesleukin
2ASULFATE IONnon-polymer96.11Chemie (SO4)
3A, B2-CYCLOHEXYL-N-(2-{4-[5-(2,3-DICHLORO-PHENYL)-2H-PYRAZOL-3-YL]-PIPERIDIN-1-YL}-2-OXO-ETHYL)-2-GUANIDINO-ACETAMIDEnon-polymer534.52Chemie (FRB)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight30872.0
Non-Polymers*Number of molecules3
Total formula weight1165.0
All*Total formula weight32037.0
*Water molecules are not included.

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PDB entries from 2024-07-17

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