1PW6

Low Micromolar Small Molecule Inhibitor of IL-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interleukin-2	polymer	133	15436.0	2	UniProt (P60568) Pfam (PF00715)	Homo sapiens (human)	IL-2, T-cell growth factor, TCGF, Aldesleukin
2	C (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	D, E (A, B)	2-CYCLOHEXYL-N-(2-{4-[5-(2,3-DICHLORO-PHENYL)-2H-PYRAZOL-3-YL]-PIPERIDIN-1-YL}-2-OXO-ETHYL)-2-GUANIDINO-ACETAMIDE	non-polymer		534.5	2	Chemie (FRB)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30872.0
Non-Polymers*	Number of molecules	3
	Total formula weight	1165.0
All*	Total formula weight	32037.0

*Water molecules are not included.