1PW6
Low Micromolar Small Molecule Inhibitor of IL-2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Interleukin-2 | polymer | 133 | 15436.0 | 2 | UniProt (P60568) Pfam (PF00715) In PDB | Homo sapiens (human) | IL-2, T-cell growth factor, TCGF, Aldesleukin |
2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
3 | A, B | 2-CYCLOHEXYL-N-(2-{4-[5-(2,3-DICHLORO-PHENYL)-2H-PYRAZOL-3-YL]-PIPERIDIN-1-YL}-2-OXO-ETHYL)-2-GUANIDINO-ACETAMIDE | non-polymer | 534.5 | 2 | Chemie (FRB) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30872.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1165.0 | |
All* | Total formula weight | 32037.0 |