1PVN

The crystal structure of the complex between IMP dehydrogenase catalytic domain and a transition state analogue MZP

Replaces:  1MWF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Inosine-5'-monophosphate dehydrogenase	polymer	376	41212.9	4	UniProt (P50097) Pfam (PF00478)	Tritrichomonas foetus	IMP dehydrogenase, IMPDH, IMPD
2	E, F, G, K, L... (A, B, C, D)	POTASSIUM ION	non-polymer		39.1	8	Chemie (K)
3	H, M, R, U (A, B, C, D)	4-CARBAMOYL-1-BETA-D-RIBOFURANOSYL-IMIDAZOLIUM-5-OLATE-5'-PHOSPHATE	non-polymer		337.2	4	Chemie (MZP)
4	I, J, N, O, S... (A, B, C, D)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	6	Chemie (TRS)
5	W, X, Y, Z (A, B, C, D)	water	water		18.0	970	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 100 (UniProt: P50097)
A, B, C, D: 227 - 503 (UniProt: P50097)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164851.7
Non-Polymers*	Number of molecules	18
	Total formula weight	2394.4
All*	Total formula weight	167246.0

*Water molecules are not included.