1PTW
The Crystal Structure of AMP-Bound PDE4 Suggests a Mechanism for Phosphodiesterase Catalysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | cAMP-specific phosphodiesterase PDE4D2 | polymer | 360 | 41394.8 | 4 | UniProt (Q08499) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE3, PDE43, PDE4D2 |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | A, B, C, D | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) | |||
| 4 | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 165579.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1912.2 | |
| All* | Total formula weight | 167491.2 |
