1PSK
THE CRYSTAL STRUCTURE OF AN FAB FRAGMENT THAT BINDS TO THE MELANOMA-ASSOCIATED GD2 GANGLIOSIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | ANTIBODY | polymer | 213 | 23209.7 | 1 | UniProt (P01837) Pfam (PF07654) | Mus musculus (house mouse) | |
| 2 | B (H) | ANTIBODY | polymer | 209 | 22368.9 | 1 | EMBL (Y11590) | Mus musculus (house mouse) | |
| 3 | C, D (L, H) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
H: 1 - 209 (EMBL: Y11590)
| PDB | External Database | Details |
|---|---|---|
| Pro 14 | Thr 14 | conflict |
| Thr 24 | Ala 24 | conflict |
| Thr 28 | Ser 28 | conflict |
| Lys 31 | Ser 31 | conflict |
| Thr 33 | Tyr 33 | conflict |
| His 35 | Tyr 35 | conflict |
| Asp 50 | Tyr 50 | conflict |
| Asn 52 | Ser 52 | conflict |
| Pro 53 | Cys 53 | conflict |
| Asn 54 | Tyr 54 | conflict |
| Gly 57 | Ala 57 | conflict |
| Asn 59 | Thr 59 | conflict |
| Gln 62 | Arg 62 | conflict |
| Thr 67 | Lys 67 | conflict |
| Leu 70 | Phe 70 | conflict |
| His 73 | Asp 73 | conflict |
| Lys 74 | Thr 74 | conflict |
| Thr 77 | Ser 77 | conflict |
| Glu 82 | Gln 82 | conflict |
| Leu 83 | Phe 83 | conflict |
| Arg 84 | Asn 84 | conflict |
| - | Ala 97 | deletion |
| - | Arg 98 | deletion |
| - | His 99 | deletion |
| Thr 97 | Tyr 100 | conflict |
| Ser 98 | Tyr 101 | conflict |
| Lys 99 | Gly 102 | conflict |
| - | Pro 104 | deletion |
| Phe 101 | Leu 105 | conflict |
| Ala 136 | Ser 140 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45578.6 | |
| All* | Total formula weight | 45578.6 |
