1PSA
STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PEPSIN A | polymer | 326 | 34513.5 | 2 | UniProt (P00791) Pfam (PF00026) | Sus scrofa (pig) | |
| 2 | C, D (A, B) | N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide | non-polymer | 541.8 | 2 | BIRD (PRD_000378) Chemie (0ZL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 326 (UniProt: P00791)
| PDB | External Database | Details |
|---|---|---|
| - | Ile 289 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69027.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1083.5 | |
| All* | Total formula weight | 70110.5 |
