1PQU
Crystal Structure of the H277N Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae Bound with NADP, S-methyl cysteine sulfoxide and cacodylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aspartate-semialdehyde dehydrogenase | polymer | 371 | 40559.7 | 4 | UniProt (P44801) Pfam (PF01118) Pfam (PF02774) | Haemophilus influenzae Rd | ASA dehydrogenase, ASADH |
| 2 | E, H, K, M (A, B, C, D) | CACODYLATE ION | non-polymer | 137.0 | 4 | Chemie (CAC) | |||
| 3 | F, I, N (A, B, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 3 | Chemie (NAP) | |||
| 4 | G, J, L, O (A, B, C, D) | CYSTEINE | non-polymer | 121.2 | 4 | Chemie (CYS) | |||
| 5 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 799 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 371 (UniProt: P44801)
| PDB | External Database | Details |
|---|---|---|
| Asn 277 | His 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 162238.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3262.8 | |
| All* | Total formula weight | 165501.6 |
