1PL6
Human SDH/NADH/inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Sorbitol dehydrogenase | polymer | 356 | 38604.5 | 4 | UniProt (Q00796) Pfam (PF08240) Pfam (PF00107) In PDB | Homo sapiens (human) | L-iditol 2-dehydrogenase |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | A, B, C, D | 4-[2-(HYDROXYMETHYL)PYRIMIDIN-4-YL]-N,N-DIMETHYLPIPERAZINE-1-SULFONAMIDE | non-polymer | 301.4 | 4 | Chemie (572) | |||
| 5 | water | water | 18.0 | 1213 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 356 (UniProt: Q00796)
| PDB | External Database | Details |
|---|---|---|
| Mse 38 | Met 38 | MODIFIED RESIDUE |
| Mse 65 | Met 65 | MODIFIED RESIDUE |
| Mse 107 | Met 107 | MODIFIED RESIDUE |
| Mse 185 | Met 185 | MODIFIED RESIDUE |
| Mse 194 | Met 194 | MODIFIED RESIDUE |
| Gln 238 | Leu 238 | SEE REMARK 999 |
| Mse 278 | Met 278 | MODIFIED RESIDUE |
| Mse 309 | Met 309 | MODIFIED RESIDUE |
| Mse 346 | Met 346 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 154417.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4120.8 | |
| All* | Total formula weight | 158538.7 |
