1PJS
The co-crystal structure of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis, in complex with it NAD cofactor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Siroheme synthase | polymer | 457 | 50286.5 | 2 | UniProt (P25924) Pfam (PF13241) Pfam (PF14824) Pfam (PF10414) Pfam (PF00590) | Salmonella typhimurium | CysG |
| 2 | C, H (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (177678424) PubChem (52224398) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (6419189) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (164157219) PubChem (118374891) PubChem (118560068) PubChem (5284331) PubChem (126969526) PubChem (129105892) PubChem (71170554) PubChem (143518505) PubChem (154578335) PubChem (13231890) PubChem (163054214) PubChem (163335525) | |||
| 3 | D, I (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | E, F (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 5 | G (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 457 (UniProt: P25924)
| PDB | External Database | Details |
|---|---|---|
| Sep 128 | Ser 128 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100573.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2491.0 | |
| All* | Total formula weight | 103063.9 |
