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1PJS

The co-crystal structure of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis, in complex with it NAD cofactor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BSiroheme synthasepolymer45750286.52UniProt (P25924)
Pfam (PF13241)
Pfam (PF14824)
Pfam (PF10414)
Pfam (PF00590)
In PDB
Salmonella typhimuriumCysG
2A, BS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
3A, BNICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.42Chemie (NAD)
4ATRIETHYLENE GLYCOLnon-polymer150.22Chemie (PGE)
5BPHOSPHATE IONnon-polymer95.01Chemie (PO4)
6waterwater18.0212Chemie (HOH)
Sequence modifications
A, B: 1 - 457 (UniProt: P25924)
PDBExternal DatabaseDetails
Sep 128Ser 128modified residue
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight100573.0
Non-Polymers*Number of molecules7
Total formula weight2491.0
All*Total formula weight103063.9
*Water molecules are not included.

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PDB entries from 2024-03-27

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