1PFG
Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proteinase K | polymer | 279 | 28958.8 | 1 | UniProt (P06873) Pfam (PF00082) | Engyodontium album | |
| 2 | B (B) | N-Ac-PAPFAAAA-NH2 | polymer | 10 | 738.9 | 1 | |||
| 3 | C, D (A, B) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 1 - 279 (UniProt: P06873)
| PDB | External Database | Details |
|---|---|---|
| Val 85 | Ala 190 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29697.7 | |
| All* | Total formula weight | 29697.7 |
