1P8J

CRYSTAL STRUCTURE OF THE PROPROTEIN CONVERTASE FURIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Furin precursor	polymer	471	51151.3	8	UniProt (P23188) Pfam (PF00082) Pfam (PF01483)	Mus musculus (house mouse)	Paired basic amino acid residue cleaving enzyme, PACE, Dibasic processing enzyme
2	I, J, K, L, M... (J, K, L, M, N...)	DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR	polymer	6	749.5	8	BIRD (PRD_000278)
3	Q (I)	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1990.8	1	In PDB GlyTouCan (G26897XI)
4	R (O)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
5	GA, IB, PC, S, UB... (B, E, H, A, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
6	HA, HC, IA, IC, JB... (B, G, E, C, H...)	CALCIUM ION	non-polymer		40.1	16	Chemie (CA)
7	AA, AB, AC, AD, BA... (A, D, F, L, M...)	SULFATE ION	non-polymer		96.1	70	Chemie (SO4)
8	GD, HD, ID, JD, KD... (A, B, C, D, E...)	water	water		18.0	2305	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	415206.3
Branched	Number of molecules	2
	Total formula weight	2723.5
Non-Polymers*	Number of molecules	92
	Total formula weight	8692.9
All*	Total formula weight	426622.7

*Water molecules are not included.