1P45
Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28554.8 | 2 | UniProt (P0A5Y6) Pfam (PF13561) UniProt (by SIFTS) (P9WGR1) | Mycobacterium tuberculosis | NADH-dependent enoyl-ACP reductase |
| 2 | C, F (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, E, G (A, B) | TRICLOSAN | non-polymer | 289.5 | 3 | Chemie (TCL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57109.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2195.5 | |
| All* | Total formula weight | 59305.0 |
