1P14
Crystal structure of a catalytic-loop mutant of the insulin receptor tyrosine kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | insulin receptor | polymer | 306 | 34792.7 | 1 | UniProt (P06213) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | B (A) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A: 978 - 1283 (UniProt: P06213)
| PDB | External Database | Details |
|---|---|---|
| Ser 981 | Cys 996 | engineered mutation |
| Asn 1132 | Asp 1147 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34792.7 | |
| All* | Total formula weight | 34792.7 |
