1OY7
Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Baculoviral IAP repeat-containing protein 7 | polymer | 140 | 15749.4 | 5 | UniProt (Q96CA5) Pfam (PF00653) | Homo sapiens (human) | Kidney inhibitor of apoptosis protein, KIAP, Melanoma inhibitor of apoptosis protein, ML-IAP, Livin |
| 2 | F (F) | AEVVAVKSE peptide | polymer | 9 | 932.0 | 1 | |||
| 3 | G, H, I, J, L (A, B, C, D, E) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 4 | K (D) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 1 | Chemie (P33) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 403 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 63 - 179 (UniProt: Q96CA5)
| PDB | External Database | Details |
|---|---|---|
| Met 40 | - | expression tag |
| Gly 41 | - | expression tag |
| Ser 42 | - | expression tag |
| Ser 43 | - | expression tag |
| His 44 | - | expression tag |
| His 45 | - | expression tag |
| His 46 | - | expression tag |
| His 47 | - | expression tag |
| His 48 | - | expression tag |
| His 49 | - | expression tag |
| Ser 50 | - | expression tag |
| Ser 51 | - | expression tag |
| Gly 52 | - | expression tag |
| Leu 53 | - | expression tag |
| Val 54 | - | expression tag |
| Pro 55 | - | expression tag |
| Arg 56 | - | expression tag |
| Gly 57 | - | expression tag |
| Ser 58 | - | expression tag |
| His 59 | - | expression tag |
| Met 60 | - | expression tag |
| Leu 61 | - | expression tag |
| Glu 62 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 79679.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 653.4 | |
| All* | Total formula weight | 80332.5 |
