1OY7

Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP)

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1001

Chain	Residue
A	CYS124
A	CYS127
A	HIS144
A	CYS151

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1002

Chain	Residue
B	CYS124
B	CYS127
B	HIS144
B	CYS151

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 1003

Chain	Residue
C	CYS127
C	HIS144
C	CYS151
C	CYS124

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 1004

Chain	Residue
D	CYS124
D	CYS127
D	HIS144
D	CYS151

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 1005

Chain	Residue
E	CYS124
E	CYS127
E	HIS144
E	CYS151

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE P33 D 1300

Chain	Residue
A	PHE81
A	TYR128
B	PHE81
B	GLY83
B	TYR128
C	TYR128
D	ALA80
D	PHE81
D	PHE114
D	THR116
D	TYR128
D	HOH1331
D	HOH1332
D	HOH1347
D	HOH1359
D	HOH1391
D	HOH1392

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR CHAIN F OF AEVVAVKSE PEPTIDE

Chain	Residue
D	ARG136
E	GLY130
E	LEU131
E	GLN132
E	SER133
E	ASP138
E	GLU143
E	TRP147
E	HOH1068
E	HOH1093
F	HOH183

---

Functional Information from PROSITE/UniProt

site_id	PS01282
Number of Residues	68
Details	BIR_REPEAT_1 BIR repeat. EelRlasfyd.Wpltaevppellaa.AGFfHtghqDkvrCffCygglqsWkrgddpwteHakwfPsCqfL

Chain	Residue	Details
A	GLU87-LEU154

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	325
Details	Repeat: {"description":"BIR"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {}

Chain

Residue

Details

---