1OWH
Substituted 2-Naphthamidine Inhibitors of Urokinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Urokinase-type plasminogen activator | polymer | 245 | 27636.5 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (human) | uPA, U-plasminogen activator |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE | non-polymer | 318.4 | 1 | Chemie (239) | |||
| 4 | F (A) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 1 - 245 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Gln 156 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27636.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 606.6 | |
| All* | Total formula weight | 28243.1 |
