1OO3
P395S mutant of the p85 regulatory subunit of the N-terminal src homology 2 domain of PI3-Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 3-kinase regulatory alpha subunit | polymer | 111 | 12860.3 | 1 | UniProt (P23727) Pfam (PF00017) In PDB | Bos taurus (cattle) | PI3-kinase p85-alpha subunit |
Sequence modifications
A: 1 - 111 (UniProt: P23727)
| PDB | External Database | Details |
|---|---|---|
| Ser 60 | Leu 380 | conflict |
| Ser 75 | Pro 395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12860.3 | |
| All* | Total formula weight | 12860.3 |
