1ODX
HIV-1 Proteinase mutant A71T, V82A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10805.7 | 2 | UniProt (P04585) Pfam (PF00077) | Human immunodeficiency virus 1 (HIV-1) | RETROPEPSIN |
| 2 | C (A) | di-tert-butyl {iminobis[(2S,3S)-3-hydroxy-1-phenylbutane-4,2-diyl]}biscarbamate | non-polymer | 543.7 | 1 | Chemie (0E8) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Ile 3 | Val 491 | conflict |
| Thr 71 | Ala 559 | engineered mutation |
| Ala 82 | Val 570 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21611.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 543.7 | |
| All* | Total formula weight | 22155.2 |
