1O79
Structures of human oxidosqualene cyclase inhibitors bound to an homologous enzyme
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | SQUALENE--HOPENE CYCLASE | polymer | 631 | 71650.0 | 3 | UniProt (P33247) Pfam (PF00432) Pfam (PF13243) In PDB | ALICYCLOBACILLUS ACIDOCALDARIUS | SHC |
2 | A, B, C | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE | non-polymer | 306.4 | 3 | Chemie (C8E) | |||
3 | A, B, C | METHYL-[4-(4-PIPERIDINE-1-YLMETHYL-PHENYL)-CYCLOHEXYL]-CARBAMINIC ACID-(4-CHLOROPHENYL)-ESTER | non-polymer | 441.0 | 3 | Chemie (R23) | |||
4 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 214950.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2242.3 | |
All* | Total formula weight | 217192.4 |