1O68

Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	3-methyl-2-oxobutanoate hydroxymethyltransferase	polymer	275	29879.0	5	UniProt (Q9JZW6) Pfam (PF02548)	Neisseria meningitidis serogroup B	Ketopantoate hydroxymethyltransferase
2	F, H, J, L (A, B, D, E)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
3	G, I, K, M (A, B, D, E)	3-METHYL-2-OXOBUTANOIC ACID	non-polymer		116.1	4	Chemie (KIV)
4	N, O, P, Q, R (A, B, C, D, E)	water	water		18.0	583	Chemie (HOH)

Sequence modifications

A, B, C, D, E: 2 - 263 (UniProt: Q9JZW6)

PDB	External Database	Details
Mse -1	-	cloning artifact
Ser 0	-	cloning artifact
Leu 1	-	cloning artifact
Mse 10	Met 10	modified residue
Mse 19	Met 19	modified residue
Mse 31	Met 31	modified residue
Mse 38	Met 38	modified residue
Mse 47	Met 47	modified residue
Mse 63	Met 63	modified residue
Mse 78	Met 78	modified residue
Mse 103	Met 103	modified residue
Mse 109	Met 109	modified residue
Mse 118	Met 118	modified residue
Mse 127	Met 127	modified residue
Mse 178	Met 178	modified residue
Mse 213	Met 213	modified residue
Mse 216	Met 216	modified residue
Mse 232	Met 232	modified residue
Glu 264	-	cloning artifact
Gly 265	-	cloning artifact
Gly 266	-	cloning artifact
Ser 267	-	cloning artifact
His 268	-	cloning artifact
His 269	-	cloning artifact
His 270	-	cloning artifact
His 271	-	cloning artifact
His 272	-	cloning artifact
His 273	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	149394.9
Non-Polymers*	Number of molecules	8
	Total formula weight	556.4
All*	Total formula weight	149951.3

*Water molecules are not included.