1O5W

The structure basis of specific recognitions for substrates and inhibitors of rat monoamine oxidase A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Amine oxidase [flavin-containing] A	polymer	534	60613.9	4	UniProt (P21396) Pfam (PF01593)	Rattus norvegicus (Norway rat)	Monoamine oxidase, MAO-A
2	E, G, I, K (A, B, C, D)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	4	Chemie (FAD)
3	F, H, J, L (A, B, C, D)	N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE	non-polymer		272.2	4	Chemie (MLG)

Sequence modifications

A, B, C, D: 1 - 526 (UniProt: P21396)

PDB	External Database	Details
Met -7	-	expression tag
Gly -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 17	Gly 17	SEE REMARK 999
Val 18	Leu 18	SEE REMARK 999
Leu 361	Gln 361	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	242455.5
Non-Polymers*	Number of molecules	8
	Total formula weight	4230.9
All*	Total formula weight	246686.4

*Water molecules are not included.