1O5R
Crystal structure of adenosine deaminase complexed with a potent inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Adenosine deaminase | polymer | 356 | 40341.7 | 1 | UniProt (P56658) Pfam (PF00962) In PDB | Bos taurus (cattle) | Adenosine aminohydrolase |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | 1-[(1R)-3-(6-{[(BENZYLAMINO)CARBONYL]AMINO}-1H-INDOL-1-YL)-1-(HYDROXYMETHYL)PROPYL]-1H-IMIDAZOLE-4-CARBOXAMIDE | non-polymer | 446.5 | 1 | Chemie (FR9) | |||
4 | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A: 2 - 357 (UniProt: P56658)
PDB | External Database | Details |
---|---|---|
Asp 8 | Asn 7 | SEE REMARK 999 |
Lys 32 | Arg 31 | SEE REMARK 999 |
Arg 33 | Lys 32 | SEE REMARK 999 |
Thr 57 | Ser 56 | SEE REMARK 999 |
Asp 60 | Glu 59 | SEE REMARK 999 |
Asp 77 | Glu 76 | SEE REMARK 999 |
Ile 79 | Val 78 | SEE REMARK 999 |
Gln 199 | Lys 198 | SEE REMARK 999 |
Thr 246 | Ala 245 | SEE REMARK 999 |
Ile 261 | Val 260 | SEE REMARK 999 |
Ala 279 | Pro 278 | SEE REMARK 999 |
Ile 281 | Val 280 | SEE REMARK 999 |
Lys 313 | Asn 312 | SEE REMARK 999 |
Asp 314 | Glu 313 | SEE REMARK 999 |
Arg 352 | Gly 351 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40341.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 511.9 | |
All* | Total formula weight | 40853.6 |