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1NZ7

POTENT, SELECTIVE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B USING A SECOND PHOSPHOTYROSINE BINDING SITE, complexed with compound 19.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProtein-tyrosine phosphatase, non-receptor type 1polymer32137365.61UniProt (P18031)
Pfam (PF00102)
In PDB
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2A2-[(4-{2-ACETYLAMINO-2-[4-(1-CARBOXY-3-METHYLSULFANYL-PROPYLCARBAMOYL)-BUTYLCARBAMOYL]-ETHYL}-2-ETHYL-PHENYL)-OXALYL-AM INO]-BENZOIC ACIDnon-polymer672.71Chemie (901)
3waterwater18.0215Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37365.6
Non-Polymers*Number of molecules1
Total formula weight672.7
All*Total formula weight38038.4
*Water molecules are not included.

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PDB entries from 2024-09-18

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