1NUO
Two RTH Mutants with Impaired Hormone Binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Thyroid hormone receptor beta-1 | polymer | 261 | 29509.1 | 1 | UniProt (P10828) Pfam (PF00104) In PDB | Homo sapiens (human) | |
| 2 | A | [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | non-polymer | 621.9 | 1 | Chemie (4HY) |
Sequence modifications
A: 201 - 461 (UniProt: P10828)
| PDB | External Database | Details |
|---|---|---|
| Asp 247 | Glu 248 | conflict |
| His 316 | Arg 316 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29509.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 621.9 | |
| All* | Total formula weight | 30131.1 |
