1NO9
Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Alpha Thrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (H) | Alpha Thrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (I) | hirugen | polymer | 11 | 1491.5 | 1 | UniProt (P28501) UniProt (by SIFTS) (P01050) | Hirudo medicinalis | N-ACETYLHIRUDIN 53 - 64 WITH SULFATO-TYR 63, Hirudin I Fragments |
| 4 | D (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (H) | N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINE | non-polymer | 269.3 | 1 | Chemie (4ND) | |||
| 6 | F, G, H (L, H, I) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35368.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 490.5 | |
| All* | Total formula weight | 35858.8 |
