1NMM
beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc
Replaces: 1JN8Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | ALPHA-LACTALBUMIN | polymer | 123 | 14015.8 | 2 | UniProt (P29752) Pfam (PF00062) In PDB | Mus musculus (house mouse) | lactalbumin, alpha |
2 | B, D | BETA-1,4-GALACTOSYLTRANSFERASE | polymer | 286 | 32849.6 | 2 | UniProt (P08037) Pfam (PF13733) Pfam (PF02709) In PDB | Bos taurus (cattle) | B4gal-t1; BETA4GAL-T1; BETA-1,4-GALTASE 1; BETA-1,4-GALACTOSYLTRANSFERASE 1; UDP-GALACTOSE:BETA-N-ACETYLGLUCOSAMINE BETA-1,4-GALACTOSYLTRANSFERASE 1 |
3 | A, C | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
4 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | D | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
6 | water | water | 18.0 | 782 | Chemie (HOH) |
Sequence modifications
B, D: 130 - 402 (UniProt: P08037)
PDB | External Database | Details |
---|---|---|
Ala 117 | - | SEE REMARK 999 |
Ser 118 | - | SEE REMARK 999 |
Met 119 | - | SEE REMARK 999 |
Thr 120 | - | SEE REMARK 999 |
Gly 121 | - | SEE REMARK 999 |
Gly 122 | - | SEE REMARK 999 |
Gln 123 | - | SEE REMARK 999 |
Gln 124 | - | SEE REMARK 999 |
Met 125 | - | SEE REMARK 999 |
Gly 126 | - | SEE REMARK 999 |
Arg 127 | - | SEE REMARK 999 |
Gly 128 | - | SEE REMARK 999 |
Ser 129 | - | SEE REMARK 999 |
Thr 342 | Cys 269 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 93730.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 911.0 | |
All* | Total formula weight | 94641.9 |