1NIW

Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	calmodulin	polymer	148	17143.4	4	UniProt (P62161) Pfam (PF13499) UniProt (by SIFTS) (P0DP29) In PDB	Rattus norvegicus (Norway rat)
2	B, D, F, H	Nitric-oxide synthase, endothelial	polymer	20	2183.6	4	UniProt (P29474) In PDB		EC-NOS, NOS (type III), NOSIII, Endothelial NOS, eNOS, Constitutive NOS, cNOS
3	G, A, C, E	CALCIUM ION	non-polymer		40.1	16	Chemie (CA)
4	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	C, E	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6		water	water		18.0	263	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 148 (UniProt: P62161)

PDB	External Database	Details
Mse 36	Met 37	MODIFIED RESIDUE
Mse 51	Met 52	MODIFIED RESIDUE
Mse 71	Met 72	MODIFIED RESIDUE
Mse 72	Met 73	MODIFIED RESIDUE
Mse 76	Met 77	MODIFIED RESIDUE
Mse 109	Met 110	MODIFIED RESIDUE
Mse 124	Met 125	MODIFIED RESIDUE
Mse 144	Met 145	MODIFIED RESIDUE
Mse 145	Met 146	MODIFIED RESIDUE

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	77308.2
Non-Polymers*	Number of molecules	21
	Total formula weight	985.6
All*	Total formula weight	78293.8

*Water molecules are not included.