1NHE

Crystal structure of Lactose synthase complex with UDP

Replaces:  1J94

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	ALPHA-LACTALBUMIN	polymer	123	14015.8	2	UniProt (P29752) Pfam (PF00062) In PDB	Mus musculus (house mouse)	LACTALBUMIN, ALPHA
2	B, D	BETA-1,4-GALACTOSYLTRANSFERASE	polymer	286	33367.5	2	UniProt (P08037) Pfam (PF13733) Pfam (PF02709) In PDB	Bos taurus (cattle)	B4GAL-T1; BETA4GAL-T1; BETA-1,4-GALTASE 1; BETA-1,4-GALACTOSYLTRANSFERASE 1; UDP-GALACTOSE:BETA-N-ACETYLGLUCOSAMINE BETA-1,4-GALACTOSYLTRANSFERASE 1
3	A, C	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A, C	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
5	B, D	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	2	Chemie (UDP)
6		water	water		18.0	331	Chemie (HOH)

Sequence modifications

B, D: 130 - 402 (UniProt: P08037)

PDB	External Database	Details
Ala 117	-	SEE REMARK 999
Ser 118	-	SEE REMARK 999
Mse 119	-	SEE REMARK 999
Thr 120	-	SEE REMARK 999
Gly 121	-	SEE REMARK 999
Gly 122	-	SEE REMARK 999
Gln 123	-	SEE REMARK 999
Gln 124	-	SEE REMARK 999
Mse 125	-	SEE REMARK 999
Gly 126	-	SEE REMARK 999
Arg 127	-	SEE REMARK 999
Gly 128	-	SEE REMARK 999
Ser 129	-	SEE REMARK 999
Mse 145	Met 72	CLONING ARTIFACT
Mse 174	Met 101	CLONING ARTIFACT
Mse 225	Met 152	CLONING ARTIFACT
Mse 258	Met 185	CLONING ARTIFACT
Mse 277	Met 204	CLONING ARTIFACT
Mse 330	Met 257	CLONING ARTIFACT
Mse 344	Met 271	CLONING ARTIFACT
Mse 370	Met 297	CLONING ARTIFACT
Mse 381	Met 308	CLONING ARTIFACT

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94766.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1276.9
All*	Total formula weight	96043.5

*Water molecules are not included.