1NH3
Human Topoisomerase I Ara-C Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3' | polymer | 10 | 3017.0 | 1 | |||
| 2 | B (C) | 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3' | polymer | 12 | 3564.4 | 1 | |||
| 3 | C (D) | 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3' | polymer | 22 | 6580.1 | 1 | |||
| 4 | D (A) | DNA topoisomerase I | polymer | 563 | 66733.9 | 1 | UniProt (P11387) Pfam (PF02919) Pfam (PF01028) Pfam (PF14370) | Homo sapiens (human) | |
| 5 | E, F, G, H (B, C, D, A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 203 - 765 (UniProt: P11387)
| PDB | External Database | Details |
|---|---|---|
| Met 699 | - | initiating methionine |
| Ptr 723 | Tyr 722 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 79895.4 | |
| All* | Total formula weight | 79895.4 |
