1NF3
Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | G25K GTP-binding protein, placental isoform | polymer | 195 | 21566.9 | 2 | UniProt (P60953) Pfam (PF00071) | Homo sapiens (human) | GP, CDC42 homolog |
| 2 | C, D (C, D) | PAR-6B | polymer | 128 | 14175.4 | 2 | UniProt (Q9JK83) Pfam (PF00595) | Mus musculus (house mouse) | |
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 423 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 191 (UniProt: P60953)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Met -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Leu 61 | Gln 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71484.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 72577.7 |
