1NCD
REFINED CRYSTAL STRUCTURE OF THE INFLUENZA VIRUS N9 NEURAMINIDASE-NC41 FAB COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (N) | INFLUENZA A SUBTYPE N9 NEURAMINIDASE | polymer | 389 | 43753.7 | 1 | UniProt (P05803) Pfam (PF00064) | Influenza A virus | |
| 2 | B (L) | IGG2A-KAPPA NC41 FAB (LIGHT CHAIN) | polymer | 214 | 23722.3 | 1 | EMBL (Y11589) | Mus musculus (house mouse) | |
| 3 | C (H) | IGG2A-KAPPA NC41 FAB (HEAVY CHAIN) | polymer | 221 | 23668.4 | 1 | UniProt (P01865) Pfam (PF07654) | Mus musculus (house mouse) | |
| 4 | D (A) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G01760ZU) | |||
| 5 | E (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F (N) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G (N) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | H, I, J (N, L, H) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
L: 1 - 214 (EMBL: Y11589)
| PDB | External Database | Details |
|---|---|---|
| Thr 20 | Ser 20 | conflict |
| Ile 21 | Val 21 | conflict |
| Asp 28 | Ile 28 | conflict |
| Ser 30 | Gly 30 | conflict |
| Ala 32 | Asn 32 | conflict |
| Val 34 | Ala 34 | conflict |
| Leu 46 | Ala 46 | conflict |
| Trp 50 | Ser 50 | conflict |
| Thr 53 | Tyr 53 | conflict |
| His 55 | Tyr 55 | conflict |
| Ile 56 | Ser 56 | conflict |
| Ala 63 | Thr 63 | conflict |
| Tyr 71 | Phe 71 | conflict |
| Ser 77 | Asn 77 | conflict |
| Ala 80 | Ser 80 | conflict |
| Leu 85 | Glu 85 | conflict |
| Tyr 87 | Phe 87 | conflict |
| His 91 | Tyr 91 | conflict |
| Tyr 92 | Asn 92 | conflict |
| Ser 93 | Arg 93 | conflict |
| Pro 94 | Tyr 94 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 91144.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1497.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 261.3 | |
| All* | Total formula weight | 92903.0 |
