1NCD

REFINED CRYSTAL STRUCTURE OF THE INFLUENZA VIRUS N9 NEURAMINIDASE-NC41 FAB COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
N	0004308	molecular_function	exo-alpha-sialidase activity
N	0005975	biological_process	carbohydrate metabolic process
N	0016020	cellular_component	membrane
N	0033644	cellular_component	host cell membrane
N	0046761	biological_process	viral budding from plasma membrane
N	0055036	cellular_component	virion membrane

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CsCygEqaGVtC

Chain	Residue	Details
N	CYS278-CYS289

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
N	ASP151

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
N	TYR406

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site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
N	ARG118
N	ARG152
N	GLU276
N	ARG292
N	ARG371

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7994573

Chain	Residue	Details
N	ASP293
N	GLY297
N	ASP324
N	ASN347

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7517697, ECO:0000269|PubMed:7994573

Chain	Residue	Details
N	ASN86

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site_id	SWS_FT_FI6
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7994573

Chain	Residue	Details
N	ASN146

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site_id	SWS_FT_FI7
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
N	ASN200

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
N	ASP151
N	GLU277

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site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
N	GLU277
N	ASP151
N	ARG220
N	TRP412
N	ARG371

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