1NC6
Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Trypsinogen | polymer | 223 | 23324.3 | 1 | UniProt (P00760) Pfam (PF00089) | Bos taurus (cattle) | beta-trypsin |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | (2S,4R)-1-ACETYL-N-[(1S)-4-[(AMINOIMINOMETHYL)AMINO]-1-(2-BENZOTHIAZOLYLCARBONYL)BUTYL]-4-HYDROXY-2-PYRROLIDINECARBOXAMIDE | non-polymer | 446.5 | 1 | Chemie (ABB) | |||
| 5 | E (A) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23324.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 582.7 | |
| All* | Total formula weight | 23907.0 |
