1N94
Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein farnesyltransferase alpha subunit | polymer | 315 | 38028.8 | 1 | UniProt (Q04631) Pfam (PF01239) | Rattus norvegicus (Norway rat) | CAAX farnesyl transferase alpha subunit, RAS proteins prenyltransferase alpha, FTase-alpha |
| 2 | B (B) | Protein farnesyltransferase beta subunit | polymer | 397 | 44478.8 | 1 | UniProt (Q02293) Pfam (PF00432) | Rattus norvegicus (Norway rat) | CAAX farnesyl transferase beta subunit, RAS proteins prenyltransferase beta, FTase-beta |
| 3 | C (A) | ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID | non-polymer | 308.4 | 1 | Chemie (HFP) | |||
| 4 | D (A) | 2-{(5-{[BUTYL-(2-CYCLOHEXYL-ETHYL)-AMINO]-METHYL}-2'-METHYL-BIPHENYL-2-CARBONYL)-AMINO]-4-METHYLSULFANYL-BUTYRIC ACID | non-polymer | 538.8 | 1 | Chemie (TIN) | |||
| 5 | E (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82507.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 912.6 | |
| All* | Total formula weight | 83420.2 |
