1N5O
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Breast cancer type 1 susceptibility protein | polymer | 214 | 24557.2 | 1 | UniProt (P38398) Pfam (PF00533) | Homo sapiens (human) | |
| 2 | B (X) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 3 | C, D (X) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (X) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
X: 1646 - 1859 (UniProt: P38398)
| PDB | External Database | Details |
|---|---|---|
| Arg 1775 | Met 1775 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24557.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 251.1 | |
| All* | Total formula weight | 24808.3 |
