1N28
Crystal structure of the H48Q mutant of human group IIA phospholipase A2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Phospholipase A2, membrane associated | polymer | 124 | 13892.0 | 2 | UniProt (P14555) Pfam (PF00068) | Homo sapiens (human) | Phosphatidylcholine 2-acylhydrolase, Group IIA phospholipase A2, GIIC sPLA2, Non-pancreatic secretory phospholipase A2, NPS-PLA2 |
| 2 | C, D, E, F (B, A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | G, H (B, A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 124 (UniProt: P14555)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | Asn 21 | engineered mutation |
| Gln 47 | His 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27783.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 27944.3 |
