1N0X
Crystal Structure of a Broadly Neutralizing Anti-HIV-1 Antibody in Complex with a Peptide Mimotope
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (L, M) | IMMUNOGLOBULIN LIGHT CHAIN | polymer | 215 | 23707.4 | 2 | UniProt (Q8TCD0) Pfam (PF07654) UniProt (by SIFTS) (P01834) | Homo sapiens (human) | IGG |
| 2 | B, D (H, K) | IMMUNOGLOBULIN HEAVY CHAIN | polymer | 230 | 24938.9 | 2 | UniProt (P0DOX5) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (human) | IGG,Immunoglobulin gamma-1 heavy chain NIE |
| 3 | E, F (P, R) | B2.1 peptide | polymer | 21 | 2546.9 | 2 | synthetic construct | ||
| 4 | G, J, K, L, M... (L, H, M, K) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | H, N, S, T (H, K, R) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | I (H) | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID | non-polymer | 221.3 | 1 | Chemie (CXS) | |||
| 7 | R (P) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 8 | U, V, W, X, Y... (L, H, M, K, P...) | water | water | 18.0 | 725 | Chemie (HOH) |
Sequence modifications
L, M: 1 - 106 (PDB: 1N0X)
L, M: 107 - 214 (UniProt: Q8TCD0)
H, K: 1 - 110 (PDB: 1N0X)
H, K: 111 - 230 (UniProt: P0DOX5)
L, M: 107 - 214 (UniProt: Q8TCD0)
| PDB | External Database | Details |
|---|---|---|
| Arg 202 | Ser 227 | conflict |
H, K: 111 - 230 (UniProt: P0DOX5)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 102386.3 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1381.4 | |
| All* | Total formula weight | 103767.7 |
