1MX9
Crystal Structure of Human Liver Carboxylesterase in complexed with naloxone methiodide, a heroin analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | liver Carboxylesterase I | polymer | 548 | 60511.3 | 12 | UniProt (P23141) Pfam (PF00135) In PDB | Homo sapiens (human) | hCEv, Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1 |
| 2 | H, I, J, K, L... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) | |||
| 3 | G, H, I, J, K... | (5A,17R)-4,5-EPOXY-3,14-DIHYDROXY-17-METHYL-6-OXO-17-(2-PROPENYL)-MORPHINANIUM | non-polymer | 342.4 | 12 | Chemie (NLX) | |||
| 4 | water | water | 18.0 | 1129 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1019 - 1567 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 726135.9 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 6984.6 | |
| All* | Total formula weight | 733120.5 |
