1MSS

LARGE SCALE STRUCTURAL REARRANGEMENTS OF THE FRONT LOOPS IN MONOMERISED TRIOSEPHOSPHATE ISOMERASE, AS DEDUCED FROM THE COMPARISON OF THE STRUCTURAL PROPERTIES OF MONOTIM AND ITS POINT MUTATION VARIANT MONOSS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	TRIOSEPHOSPHATE ISOMERASE	polymer	243	26020.7	2	UniProt (P04789) Pfam (PF00121) In PDB	Trypanosoma brucei brucei
2		water	water		18.0	56	Chemie (HOH)

Sequence modifications

A, B: 1 - 250 (UniProt: P04789)

PDB	External Database	Details
Ser 45	Phe 45	engineered mutation
Ser 46	Val 46	engineered mutation
Gly 68	Ile 68	engineered mutation
Asn 69	Ala 69	engineered mutation
Ala 70	Lys 70	engineered mutation
Asp 71	Ser 71	engineered mutation
Ala 72	Gly 72	engineered mutation
-	Ala 73	deletion
-	Phe 74	deletion
-	Thr 75	deletion
-	Glu 77	deletion
-	Val 78	deletion
-	Ser 79	deletion
Ala 81	Pro 81	engineered mutation
Ser 82	Ile 82	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52041.4
All*	Total formula weight	52041.4

*Water molecules are not included.