1MQD
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-Des-Me-AMPA at 1.46 A resolution. Crystallization in the presence of lithium sulfate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Glutamate receptor subunit 2 | polymer | 261 | 29077.6 | 4 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (Norway rat) | GluR-2 |
| 2 | A, B, D | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A, B, C, D | (S)-2-AMINO-3-(3-HYDROXY-ISOXAZOL-4-YL)PROPIONIC ACID | non-polymer | 172.1 | 4 | Chemie (SHI) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 2626 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 0 - 114 (UniProt: P19491)
A, B, C, D: 117 - 258 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116310.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1068.8 | |
| All* | Total formula weight | 117379.1 |
