1ML3
Evidences for a flip-flop catalytic mechanism of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, from its crystal structure in complex with reacted irreversible inhibitor 2-(2-phosphono-ethyl)-acrylic acid 4-nitro-phenyl ester
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glyceraldehyde 3-phosphate dehydrogenase, glycosomal | polymer | 359 | 39112.5 | 4 | UniProt (P22513) Pfam (PF00044) Pfam (PF02800) | Trypanosoma cruzi | GAPDH |
| 2 | E, G, I (B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 3 | Chemie (NAD) | |||
| 3 | F, H, J (B, C, D) | (3-FORMYL-BUT-3-ENYL)-PHOSPHONIC ACID | non-polymer | 164.1 | 3 | Chemie (CYX) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 695 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 156450.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2482.6 | |
| All* | Total formula weight | 158932.7 |
